Professional Summary
- Led AI initiatives in clinical pharmacology, integrating LLMs and multi-agent solutions for regulatory-compliant clinical data analysis
- Leadership experience managing cross-functional teams of clinical data scientists, software engineers, and IT teams in international settings
- Technical background in machine learning, biostatistics, and quantitative pharmacology with focus on regulatory-compliant AI implementations
- Academic foundation in AI/ML and computational sciences with proven track record in collaborative research and industry partnerships
- Multilingual professional with deep understanding of European research environments and pharmaceutical development processes
Work Experience
- Architected multi-agentic workflow to accelerate QSP model development
- Coordinated multidisciplinary team of 15 specialists across clinical data science, software engineering, and pharmacometrics
- Developed Clinical Pharmacology AI platform enabling agentic workflows for 60+ users working on submission-relevant analysis
- Provided strategic consultation to Clinical Pharmacology leadership team on implementing agentic workflows for departmental transformation
- Architected cloud migration strategy for clinical pharmacology department ensuring scalable computational infrastructure
- Represented Boehringer Ingelheim in cross-industry AI initiatives including clinical pharmacology AI, biomarker AI, and QSP AI (collaborations with AbbVie, Sanofi, and Roche, etc.)
- Co-founded a startup leveraging tech and machine learning for asset investment
- Developed AI-driven software that utilized fundamental and technical analysis, combined with advanced ML and statistical methods
- Successfully launched a software for effective investment portfolio management
- Coordinated Data & Tech ML activities within cross-functional working groups for machine learning strategy development
- Conducted biomarker analysis for NAFLD fibrosis stage prediction using advanced machine learning and statistical modeling approaches
- Co-led academic collaboration with the University of Tübingen on physics-informed neural networks application in systems pharmacology for Chronic Kidney Disease research
- Coordinated cross-functional team of 8 specialists (IT, Quality, Business) to establish robust computational infrastructure for TMCP data analysis teams
- Established validated computing environment leading cross-functional teams (IT, Quality, Business) for clinical data science applications
- Supervised research personnel including interns and postdoctoral researchers while publishing 20+ scientific articles including two in Nature Communications
- Established knowledge transfer programs including Pharmacometrics Knowledge Hour, providing training on R, machine learning, and advanced statistical methodologies
- Managed clinical data science projects in collaboration with external CROs, delivering analysis reports for regulatory submissions
- Applied innovative methodologies integrating physics-informed neural networks with nonlinear mixed effects models, presenting results at conferences
- Evaluated statistical and ML methods for PKPD analysis supporting clinical trial decision-making across oncology portfolio
- Participated in cross-functional working groups and coordinated industry collaborations with academic experts
- Coordinated pharmacometrics AI/ML strategic roadmap development and implementation across therapeutic areas
- Managed research team supervising 2 PhD and 8 Master's students in computational biology projects
- Co-led international consortium project SmartNanoTox with 9 European partners and €8M total funding, developing MATLAB-based computational frameworks
- Coordinated academic partnerships with Karolinska Institute and Technical University of Munich on AI solutions for inflammatory disease research
- Developed computational analysis platform for spatial transcriptomics in inflammatory skin diseases, published in Nature Communications
- Contributed as AI lead for ML-driven pharmacometrics analysis for EU project UNITE4TB, collaboration with GSK
- Managed €4M collaborative project with Fraunhofer and Max Planck Institutes on nano-drug delivery computational pharmacology
- Presented and published scientific articles in conferences and journals
- Solved partial differential equations (PDEs) using high performance computers (HPC)
- Image processing and Segmentation of 3D complex human airways from CT images
- Optimized the drug delivery device of PARI Respiratory Equipment Inc.
- Image processing and segmentation of human respiratory system from CT images
- Presented technical reports in R&D department of industrial partner
- Published and presented results in journals and conferences
- Developed software for PDEs
- Optimized the efficiency of washing drying machines of BEKO
- Teaching assistant for C++, Engineering Mathematics courses
- Top student at department of mechanical engineering (Note: 1.0)
- Full fund scholarship from Turkish Ministry of Science and Technology
- Paul Eisenklam young researcher travel award (ILASS14 Conference, Bremen, Germany)
Education
Technical Competencies
ML & GenAI
Neural Networks | Conventional ML (classification, clustering, regression) | Gen AI (LLMs, Transformers, Prompt Engineering) | Agentic AI Workflows | RAG Systems | Enterprise AI | Databricks | Cloud Computing (GxP-Compliant)
Clinical Data Science
Population PK/PD | Quantitative Pharmacology | Machine Learning | Biostatistics | Spatial Transcriptomics | Advanced Statistical Modeling
Programming & Leadership
Python, R (Advanced) | MATLAB, Julia | Cross-Functional Team Management | Academic-Industry Leadership | International Project Leadership
Languages
Certificates
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Harvard Medical School - HMX Pro Pharmacology - Clinical Drug Development
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Harvard Medical School - AI in Medicine - Natural Language Processing
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Pharmacometrics Statistics, TACA Training
Awards
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Excellence Initiative Scholarship for PhD studies (2015 – 2018)DFG (German Research Foundation)
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Best Poster Presentation Award (12/2016)HGS MathComp Annual Colloquium 2016 / Heidelberg University
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Paul Eisenklam Young Researcher Travel Award (09/2014)ILASS14 / 26th European Conference Liquid Atomization & Spray Systems
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Scholarship for Master Studies (2013 – 2015)Turkish Ministry of Science and Technology
Editorial and Reviewing Activities
Selected Scientific Publications
View complete publication list:
Google Scholar | ORCID: 0000-0002-9298-5497 | Personal Website
Recent highlights include publications in Nature Communications and CPT: Pharmacometrics & Systems Pharmacology